The Brigade was under instruction of the French in the Bourmont training area with Brigade Headquarters located at Damblain, remaining there until March 14th when it commenced movement into sub-sectors of the Verdun Front, the first units of the Brigade entering the front line during the night of March 16-17th. At that time Colonel Wendell C. Neville commanded the 5th Regiment, Colonel Albertus W. Catlin commanded the 6th Regiment and Major Edward B. Cole commanded the 6th Machine Gun Battalion.

Remained on the Verdun Front until May 14th when the Brigade proceeded to the training area around Vitry-le-Francois. In the meantime, on May 6th, Brigadier General James G. Harbord assumed command, relieving General Doyen who had been ordered to the United Stutes. On May 19th, Brigade left that area and proceeded to area around Gisors and Chaumont-en-Vexin, remaining there until May 31st when the units of the Brigade moved by camions into the sector northwest of Chateau-Thierry, going into line immediately upon its arrival, June 1st, 2nd and 3rd. During operations of the Brigade, the companies of the 6th Machine Gun Battalion were usually asaigned to Battalions of the two Regiments,

In action northwest of Chateau Thierry from June 1st to July 7th, 1918, during which the Brigade captured Bouresches, Bois de Belleau and Hill 142. Brigade was relieved July 7th and took up reserve position behind the lines just occupied until July 16th.